6 Science-Backed Supplements for a Longer, Healthier Life

The science of longevity. Discover 6 key anti-aging supplements, the ideal weekly exercise routine, and the intermittent fasting for cellular health and a longer, vibrant life

Sep 30, 2025 - 13:23
Sep 30, 2025 - 07:21
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6 Science-Backed Supplements for a Longer, Healthier Life
Learn about six science-backed dietary supplements?Resveratrol, NAD+, Omega-3, Curcumin, Coenzyme Q10, and Spermidine?for a longer, healthier life.

The Scientific Toolkit for Longevity: Six Key Supplements

The pursuit of a longer life is not merely a desire to add more years, but an ambition to increase the quality of life and maintain vitality and youth for as long as possible. Today, science is opening vast doors for us to achieve this goal. Through a deep understanding of cellular biology, researchers have discovered secrets that contribute to slowing down aging and rejuvenating the body's cells. Among the most prominent of these secrets are dietary supplements that science has proven to have a tangible effect on extending life. Here are 6 of the most powerful dietary supplements that scientific studies have shown to be effective in supporting cellular health and extending human life:

  1. Resveratrol Resveratrol is a natural compound found in the skin of red grapes, berries, and peanuts. Studies have shown that it activates proteins called sirtuins, which are responsible for protecting and repairing DNA in cells. These proteins contribute directly to extending life and delaying the signs of aging by strengthening cellular defense against oxidative stress. Notable Study: A study published in the journal Cell indicated that resveratrol can improve metabolic functions and increase the lifespan of mice by significant percentages.

  2. NAD+ NAD+ is a vital molecule involved in all energy production processes within cells. With age, its levels decrease significantly. It is believed that boosting its levels helps maintain the health of mitochondria (the cellular powerhouses), which leads to improved cellular vitality and a delay in the aging process. Notable Study: A study in the journal Science showed that increasing NAD+ levels in older mice helped improve vital organ functions and slowed down cellular aging.

  3. Omega-3 Omega-3 fatty acids, found abundantly in fatty fish like salmon and sardines, are among the essential supplements known for their positive effect on longevity. Omega-3 helps reduce chronic inflammation, which is one of the leading causes of aging and chronic diseases, such as heart disease and Alzheimer's. Notable Study: An extensive study published in the journal Nature Communications indicated that high levels of omega-3 were clearly associated with longevity and a lower rate of premature death.

  4. Curcumin Curcumin is the active ingredient found in turmeric and is distinguished by its antioxidant and anti-inflammatory properties. Curcumin helps protect cells from damage and improves their regeneration, which contributes to enhancing cellular health and slowing down aging. Notable Study: Multiple studies have confirmed that curcumin protects cells from oxidative stress and enhances the body's immune response against diseases of aging.

  5. Coenzyme Q10 Coenzyme Q10 is one of the essential components for energy production in cells, and it also acts as a powerful antioxidant. With age, its levels in the body decrease, which leads to a reduced ability of cells to rejuvenate themselves. Boosting its levels through dietary supplements is an effective way to maintain cellular vitality for a longer period. Notable Study: The journal BioFactors confirmed that CoQ10 supplements contributed significantly to improving heart health and overall body energy, and thus helped extend healthy life.

  6. Spermidine Spermidine is a natural compound found in high quantities in whole wheat, soy products, mushrooms, and some types of cheese. This compound has gained great attention in recent years due to its unique ability to activate autophagy, a natural process during which cells get rid of damaged components and constantly rejuvenate themselves, which contributes to slowing down aging and promoting longevity. Notable Study: A study published in the journal Nature Medicine showed that spermidine supplements improved cardiovascular health and significantly increased the lifespan of experimental animals. Preliminary clinical studies in humans also showed promising results in promoting general health and delaying the signs of aging.

The Longevity Lifestyle: Exercise and Advanced Nutrition

Weekly Minutes of Exercise Can Give You Extra Years of Life

Imagine if you had a simple choice that gave you renewed youth, a strong body, and extra years full of vitality and energy. This opportunity is available to you now: at least 200 minutes per week of swimming or rowing can make a real difference in your quality of life and your biological age. But why 200 minutes or more?

The American College of Sports Medicine (ACSM) issued a statement recommending at least 150 minutes of moderate-intensity physical activity per week for adults who are overweight or obese to improve their health. However, it recommended 200 to 300 minutes per week for long-term weight loss. Recent studies, especially in Saudi Arabia, have proven that the World Health Organization's recommendations (150 minutes of moderate activity or 75 minutes of high-intensity activity per week) may not be sufficient to achieve tangible results in weight loss and stimulating the vital processes that affect longevity. In contrast, it was found that increasing physical activity to 200 minutes or more per week achieves tremendous health benefits and supports weight loss in an effective and sustainable way.

What Happens in Your Body When You Exercise 200 Minutes or More Per Week?

  1. Intense Stimulation of Growth Hormone (HGH): Swimming and rowing are aerobic activities that stimulate the secretion of HGH, which decreases with age. This hormone is essential for building muscle, strengthening bones, improving skin elasticity, and burning fat more effectively, making your body more youthful for a long time.

  2. Enhancing Mitochondrial Activity (The Powerhouses of Cells): By exercising such as swimming or rowing for 200 minutes per week, you enhance the productivity of mitochondria in your body's cells, which increases your energy and improves the body's performance at the cellular level. This slows down cellular aging and boosts your overall health.

  3. Significant Reduction in Chronic Inflammation: Studies indicate that intense aerobic exercise weekly contributes to lowering levels of chronic inflammation, which is the main cause of age-related diseases like heart disease, diabetes, and Alzheimer's.

  4. Increased Fat-Burning Efficiency and Weight Loss: Unlike the usual 150-minute recommendation, research shows that exercising for 200 minutes or more per week has a clear effect on losing weight in an effective and sustainable way. Swimming and rowing burn calories with high efficiency and help build muscle mass, which increases your metabolism, making your body more capable of maintaining a healthy weight for a long time.

  5. Strengthening the Immune System and Improving Mood: Swimming and rowing enhance the body's immunity and contribute to the release of happiness hormones (endorphins, serotonin, dopamine), which reduces stress, anxiety, and depression levels, and improves your mental and psychological quality of life.

How to Easily Achieve 200 Minutes Every Week?

  • Divide these minutes into 4 or 5 sessions per week, each session lasting 40 to 50 minutes.

  • Commit to a regular schedule and make exercise a part of your daily routine.

  • Choose your favorite activity between swimming or rowing, which are gentle on the joints and effective in burning fat and promoting health.

How Intermittent Fasting and a High-Protein Diet Give You a Longer, More Vibrant Life

After we talked about essential dietary supplements and the importance of exercising for 200 minutes a week, it is time to open the door to the third secret in our journey toward a long and healthy life: the diet. Not just any diet, but the one that science has proven to be effective in resetting your body's biological clock and giving your cells a chance to rejuvenate: intermittent fasting for 20-22 hours a day with a high-protein, low-carbohydrate diet.

First: Intermittent Fasting (20-22 hours) - The Key to Rejuvenation The idea of abstaining from food for up to 22 hours a day may seem difficult at first, but this method works real miracles at the cellular level:

  1. Activating Autophagy Fasting for 20-22 hours a day activates autophagy, which allows cells to get rid of old and damaged parts and recycle them into new ones. Simply put, this process rejuvenates your body's cells from within and protects you from premature aging, and significantly reduces the risk of chronic diseases.

  2. Lowering Insulin and Cortisol Levels Long-term fasting significantly reduces the secretion of the hormone insulin, which improves the body's sensitivity to it and reduces inflammation that causes aging and chronic diseases. Fasting also reduces the hormone cortisol (the stress hormone), which slows down the aging process at the cellular level.

  3. Boosting the Secretion of Growth Hormone (HGH) Long-term intermittent fasting (20-22 hours) stimulates your body to produce an exceptional amount of growth hormone, which helps maintain muscle mass, bone strength, and skin renewal, in addition to burning fat effectively.

Second: High-Protein, Low-Carbohydrate Diet - The Diet of Eternal Youth A diet that is based on high protein and low carbohydrates is not just a diet for weight loss; it is one of the most important secrets that protects your health and supports longevity:

  1. Maintaining Strong Muscle Mass Proteins are the basic building blocks of the body. They maintain your muscle mass, which strengthens your bones and protects you from muscle weakness associated with aging. Good muscle mass also means a faster metabolism, which makes you look and live younger than your real age.

  2. Reducing Inflammation and Improving Heart Health Reducing carbohydrates lowers blood sugar and insulin levels, which reduces chronic inflammation and improves the health of the heart and arteries, and thus contributes to significantly extending life.

  3. Enhancing the Feeling of Fullness and Losing Weight Easily Eating a high-protein diet helps you feel full for longer periods, which makes it easier for you to follow intermittent fasting. In contrast, reducing carbohydrates accelerates fat burning and reduces the accumulation of harmful fats that accelerate the aging of the body.

How to Start and Succeed in Following This Diet Easily?

  • Divide your meals: Eat one large main meal, rich in protein (such as meat, fish, eggs), healthy fats (such as avocado and olive oil), and leafy vegetables, and avoid complex carbohydrates as much as possible.

  • Gradual fasting: Start with a 16-hour fast, then gradually increase it until you reach 20-22 hours.

  • Stay hydrated: Drink water, green tea, or coffee without sugar during fasting hours to boost fat burning and relieve hunger.

The Return on Investment: Immediate and Long-Term Rewards

What Will You Gain by Adopting This Lifestyle? Short- and Long-Term Benefits

If you have made it this far, it means you are seriously thinking about the most important investment in your life: your health and your longevity. The following question may come to your mind: What will I actually get if I start today by committing to the right dietary supplements, exercising for 200 minutes a week, and intermittent fasting with a high-protein, low-carbohydrate diet? The answer is simple: you will gain an exceptional life on both the short and long terms.

First: Immediate Benefits (Short-Term)

  1. A Noteworthy Increase in Energy Levels In the first days and weeks, you will feel that you have renewed energy, enabling you to accomplish your daily tasks with ease and efficiency. This is due to the improved activity of mitochondria (the energy factories in your cells), which is enhanced by both regular exercise and high-quality dietary supplements.

  2. Deeper and Better Quality Sleep Within a few weeks, your body will begin to regulate its biological clock thanks to intermittent fasting and regular physical activity, which leads to a significant improvement in sleep quality. You will wake up in the morning feeling refreshed and with renewed vitality.

  3. A Clear Improvement in Mood and Mental Health Fasting and exercise together stimulate the secretion of happiness hormones (endorphins, dopamine, serotonin), which improves mood, reduces stress and anxiety, and boosts your morale and self-confidence.

  4. Rapid Weight Loss and a Clear Improvement in Body Shape Following a high-protein, low-carbohydrate diet, with intermittent fasting, helps you lose excess fat, especially in the abdominal area, and maintains muscle mass, which gives you a well-proportioned and healthy body in a short period.

Second: Long-Term Benefits (The Real Gains)

  1. A Noteworthy Slowing of Cellular Aging By exercising regularly and taking dietary supplements that enhance cellular health (such as NAD+, resveratrol, and omega-3), you reduce oxidative stress, which contributes significantly to slowing down aging and maintaining the youthfulness of your cells for many years.

  2. Prevention of Chronic Diseases A healthy diet, intermittent fasting, and regular physical activity significantly reduce the likelihood of developing chronic diseases such as diabetes, heart disease, high blood pressure, and even some types of cancer. As you get older, you will notice that you are healthier and stronger than most people your age.

  3. Sharp Memory and Strong Cognitive Functions Intermittent fasting, a low-carbohydrate high-protein diet, and regular exercise maintain brain health, enhance the production of new nerve cells, and significantly improve your mental abilities, which means maintaining your mental independence in old age.

  4. Exceptional Quality of Life in Advanced Age Adhering to these healthy practices ensures you a long life full of vitality and activity and gives you the ability to enjoy your life and loved ones for a longer period without suffering from the diseases of old age. You will be able to travel, enjoy your hobbies, and spend precious time with your family and friends.

The Longevity Decision Is in Your Hands

Imagine yourself 5, 10, or even 20 years from today. What kind of life do you want? Do you want to enjoy excellent health, high fitness, and continuous activity and vitality? If the answer is yes, all you have to do is make a decision today. Don't wait for tomorrow, because when it comes to your health and quality of life, the best time to start is now. Start today, to live a better and brighter future.

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Dr. Nasser F BinDhim Executive Consultant | Strategy Execution & Governance Expert | Data Management & R&D Advisor. I provide executive consulting and advisory services rooted in advanced scientific thinking, deep governance expertise, and a strategic understanding of local policy ecosystems. My value lies in translating complexity into clarity, enabling leaders to make informed, high-stakes decisions with precision and confidence.